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KMID : 0356919770100010015
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Korean Journal of Anesthesiology
1977 Volume.10 No. 1 p.15 ~ p.18
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Effect of Propranolol on the Heart Rate Daring Halothane Anesthesia
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Abstract
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The decreasing effect on the heart rate of propranolol, a beta-adrenergic blocker, is well known.
This effect of propranolol was studied in conscious and anesthetized men. Propranolol in small doses (0.5㎎ and 1.0㎎) was given intravenously to fifteen conscious and ten halothane anesthatized men.
The heart rate showed definite decrease in all cases, the effect being more pronounced in the halothane anesthetized group than in the conscious group.
The bradycardia action mechanism of propranolol is different from that of small doses of the belladona alkaloids.
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